It's been working fine for me after many many reboots. I'm using a cheap Logitech cordless laser mouse. I'm using software mw9791enu.exe for my mouseware. Some setting must have changed on your system to screw it up. I have the cheap wireless Logitech keyboard too but I never loaded the Logitech software for it. I defaulted to Windows for the keyboard. Uninstall the mouseware, reboot, run Registry Mechanic, reboot and reinstall the mouseware and uncheck the box. Only thing I can think of. If it worked once it should work again; it's not human.